Job title: Sr. Research Scientist (DMPK-Bioanalytical)

Company: Jubilant Pharmova

Job description: Jubilant Biosys is hiring for: Position: Sr. Research Scientist (Bioanalytical) Department: DMPK Education/ Experience: M.Pharm with 10-13 yrs of experience is Bioanalysis for NCE’s & biologics. Key Responsibilites: * Responsible for drug metaboli

Jubilant Biosys is hiring for: Position: Sr. Research Scientist (Bioanalytical) Department: DMPK Education/ Experience: M.Pharm with 10-13 yrs of experience is Bioanalysis for NCE’s & biologics. Key Responsibilites: Responsible for drug metabolism and pharmacokinetic support for discovery programs. Support preclinical bioanalysis Monitor Pharmacokinetics studies and support bioanalysis Providing pre-clinical ADME lead optimization support to small molecule Drug Discovery programs (Hit Identification to Clinical Candidate Selection) including Inflammation, Neuroscience, Metabolic Disorders and Anti-infective Research. Working as a ‘DMPK subject matter lead’ in multidisciplinary/cross functional teams of drug discovery projects. Understand the Chemical Structure – ADME relationships and design apt strategies towards improving Drug like Properties of the New Chemical Entities. Understand the broader ADME requirements of various projects Conduct PK and PK/PD analysis through early pre-clinical development, and collaborate in PK/PD and efficacy study designs Collaborate with safety assessment group (in need basis) on study design Design tailor made ADME protocols for various projects Collate the obtained results and prepare presentations for internal and external meetings Contribute to the design of the critical path for various projects Prediction of human pharmacokinetic properties from in vitro and in vivo data Managing PK and PK/PD analysis through early pre-clinical development, and collaborates in PK/PD and efficacy study design developing robust PK/PD models Prediction of human pharmacokinetic properties from in vitro and in vivo data in preclinical species. Collaborates with safety assessment group on study design. Method validations and analytical trouble shooting Data generation, compilation, report preparation Lab note book, record keeping SOP writing Additional expertise: Bioanalysis using LC-MS/MS under GLP and non-GLP environment, can lead project as DMPK representative, quantitation of small molecule using LC-MS/MS and can perform metabolite identification work on High resolution mass spectrometry. Jubilant Drug Discovery and Development Services (JDDDS) , is part of the Jubilant LifeSciences family of companies with R&D Centers in India, USA and business offices in Asia, Europe and North America. JDDDS has a global reach and provides comprehensive drug discovery and development solutions from target discovery to clinical development in partnership with leading pharma companies worldwide. With clear scientific focus in Oncology, Metabolic Disorders, CNS and Pain and Inflammation, JDDDS has rapidly emerged as a leading collaborator for pharma industry. In each of these therapeutic areas, Jubilant has developed a depth of expertise in discovery informatics, medicinal chemistry, structural biology, biology, in vitro, in vivo models and translational sciences. Combined with strong clinical development and manufacturing capabilities, Jubilant has emerged as a fully integrated company with end-to-end solution for pharma industry. JDDDS business constitutes three Jubilant subsidiaries, Jubilant Biosys (Drug discovery services), Jubilant Chemsys (Chemistry services) and Jubilant Clinsys (Clinical trial services). With over 1200 highly skilled and experienced scientific and medical personnel spread across Bangalore and Noida in India, Europe and the US, the JDDDS vertical leverages the capabilities in emerging markets for a global outcome, accelerating the global drug development efforts.

Expected salary:

Location: Bangalore, Karnataka

Job date: Mon, 02 May 2022 22:48:38 GMT

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